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The Manic Pixie Dream Girl may be featured as the Second Love, in order to break the character out of The Mourning After.
If he's a cynic, her goal may be to convince him that Silly Rabbit, Cynicism Is for Losers! Finally, she may be presented as a cheerful variety of Threshold Guardians, all the way from less uptight to psychopomps happily welcoming their clients into "another adventure".
They are four of the most celebrated women in British film and theatre - but despite their towering reputations they have never been seen on screen together, until now.
The Screwball Comedy is a genre driven entirely by this character type.
Although not quite Always Female, a "Manic Pixie Dream Boy" is a much rarer concept.
Despite all that (or of all that), there are ways of utilizing this trope without falling into that pitfall.
Given enough time, Character Development can add to their personality and interests and pull them away from the MPDG foundation.